Custom-made orthodontic miniscrews were tested for physical property and primary stability with satisfactory results. The next step of miniscrew development was a clinical trial. The study objective was to analyze and compare the success rate of the custom-made miniscrews with those of the imported miniscrews. Patients who required two miniscrews in each quadrant of an upper arch were recruited into a single-blinded, split-mouth, randomized, controlled trial. Imported miniscrews were inserted in one side as a control group while custom-made miniscrews were inserted on the other side as an experiment group. The success rates of each of the two types of miniscrews were examined. Criteria for the success of miniscrews were an absence of mobility, lose or lost and maintained for six months. Fisher exact probability test was used to examine the correlation between the success rates and types of miniscrews. Forty-two patients were included in the study. The success rate of the imported miniscrews and custom-made miniscrews was 88.1 and 85.7 % respectively. The result was not a significant difference. Factors potentially affecting the success were investigated. There was no a significant difference in age, sex, sagittal and vertical skeletal type, and miniscrew applications. In conclusion, custom-made miniscrews have the success rate equal to those of imported miniscrews. With lower prices and reduced importation, custom-made miniscrews should be encouraged to replace the use of imported miniscrews.